Persistent hyponatraemia complicating fibrosing alveolitis.

نویسندگان

  • N J Snell
  • H L Coysh
چکیده

PATIENT 1 A previously healthy 70-year-old housewife presented with dry cough and dyspnoea. She had finger clubbing, was dyspnoeic at rest, and had basal crackles. A chest radiograph showed bilateral reticulonodular shadowing. Spirometry showed a restrictive picture; transfer factor was very low at 3 55 ml/min/mm Hg (1 19 mmol min-' kPa-1). Pao2 at rest was 55 mm Hg (7 32 kPa), Paco, 40 mm Hg (5 32 kPa). Aspergillus precipitins were absent as were antinuclear antibodies. The result of a Mantoux test was negative. Sputum cytology showed no atypical cells. Cryptogenic fibrosing alveolitis was diagnosed, and the patient started taking oral prednisolone, 10 mg daily. She was admitted to hospital four months later with increasing dyspnoea, which had been treated by her general practitioner with a thiazide diuretic. Her physical findings and chest radiograph were unchanged, and she was

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Response to methotrexate in fibrosing alveolitis associated with connective tissue disease.

Methotrexate by intermittent intramuscular injection was used to treat three patients with fibrosing alveolitis complicating connective tissue diseases. All three patients had improvement of symptoms, two had radiological improvement, and one had significant improvement of pulmonary function. Two patients whose pulmonary symptoms, function, and chest radiographs had deteriorated on penicillamin...

متن کامل

Neutrophil activation in fibrosing alveolitis: a comparison of lone cryptogenic fibrosing alveolitis and systemic sclerosis.

Fibrosing alveolitis complicating systemic sclerosis (FASSc) carries a better prognosis than lone cryptogenic fibrosing alveolitis (CFA). We wanted to determine whether this improved prognosis is associated with differential neutrophil migration and activation in the lower respiratory tract. We therefore compared bronchoalveolar lavage (BAL) neutrophil numbers and levels of neutrophil-derived e...

متن کامل

Hypothesis: exposure to solvents may cause fibrosing alveolitis.

The incidence of fibrosing alveolitis, which can be caused by many agents, is increasing. In a proportion of patients, the aetiology is unknown (cryptogenic fibrosing alveolitis), but it has been suggested that environmental factors may play an important, but unrecognized, role in its pathogenesis. A review of the literature suggests that there may be a link between exposure to solvents, widesp...

متن کامل

Fibrosing alveolitis with autoimmune haemolytic anaemia: two case reports.

Two patients with fibrosing alveolitis and autoimmune haemolytic anaemia are described. One patient also had neurofibromatosis. The haematological associations of fibrosing alveolitis are discussed, and a possible relationship between autoimmune haemolysis and fibrosing alveolitis is suggested.

متن کامل

Accuracy of diagnostic coding of hospital admissions for cryptogenic fibrosing alveolitis.

To determine the accuracy of diagnostic coding of cryptogenic fibrosing alveolitis, the case notes of 166 admissions to four hospitals were reviewed. These consisted of all admissions that had been coded as "idiopathic fibrosing alveolitis" (ICD code 516.3: 97 admissions) or as "postinflammatory pulmonary fibrosis" (ICD code 515.9: 69 admissions). Of 88 available records of admissions coded as ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Thorax

دوره 33 6  شماره 

صفحات  -

تاریخ انتشار 1978